概述

  • 产品名称Anti-Nodal抗体
    参阅全部 Nodal 一抗
  • 描述
    兔多克隆抗体to Nodal
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (PSSPSPLAYM LSLYRDPLPR ADIIRSLQAE DVAVDGQNWT FAFDFSFLSQ) of Human NODAL (NP_060525).

  • 阳性对照
    • Human fetal thymus lysate.

性能

应用

Our Abpromise guarantee covers the use of ab99196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Essential for mesoderm formation and axial patterning during embryonic development.
  • 疾病相关Defects in NODAL are the cause of visceral heterotaxy autosomal type 5 (HTX5) [MIM:270100]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy autosomal type 5 include situs inversus viscerum or situs ambiguus, congenital heart defect, transposition of the great vessels ventricular septal defect, atrial septal defect, truncuscommunis, and dextrocardia.
  • 序列相似性Belongs to the TGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HTX5 antibody
    • MGC138230 antibody
    • Nodal antibody
    • Nodal Growth Differentiation Factor antibody
    • nodal homolog (mouse) antibody
    • Nodal homolog antibody
    • Nodal, Mouse, Homolog antibody
    • NODAL_HUMAN antibody
    see all

Anti-Nodal antibody 图像

  • Anti-Nodal antibody (ab99196) at 1 µg/ml + Human fetal thymus lysate at 10 µg

    Predicted band size : 39 kDa

Anti-Nodal antibody (ab99196)参考文献

ab99196 has not yet been referenced specifically in any publications.

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