Anti-Nodal抗体(ab110162)

概述

  • 产品名称Anti-Nodal抗体
    参阅全部 Nodal 一抗
  • 描述
    山羊多克隆抗体to Nodal
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to internal region of Human Nodal conjugated to KLH.

  • 阳性对照
    • Human Brain cortex and Human Placenta tissues

性能

应用

Our Abpromise guarantee covers the use of ab110162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/32000.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Essential for mesoderm formation and axial patterning during embryonic development.
  • 疾病相关Defects in NODAL are the cause of visceral heterotaxy autosomal type 5 (HTX5) [MIM:270100]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy autosomal type 5 include situs inversus viscerum or situs ambiguus, congenital heart defect, transposition of the great vessels ventricular septal defect, atrial septal defect, truncuscommunis, and dextrocardia.
  • 序列相似性Belongs to the TGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HTX5 antibody
    • MGC138230 antibody
    • Nodal antibody
    • Nodal Growth Differentiation Factor antibody
    • nodal homolog (mouse) antibody
    • Nodal homolog antibody
    • Nodal, Mouse, Homolog antibody
    • NODAL_HUMAN antibody
    see all

Anti-Nodal antibody 图像

  • Human Brain, cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) using ab110162 at a concentration of 3.75 µg/ml.
  • Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) using ab110162 at a concentration of 3.75 µg/ml.

Anti-Nodal antibody (ab110162)参考文献

ab110162 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (Uterus)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Tris-EDTA PH9.0
Permeabilization Yes - 0.15% Triton-X-100 in PBS
Specification Uterus
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Fixative Paraformaldehyde
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提交于 Jun 15 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"