概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 序列FGGFTGARKSARKLANQ
    • 氨基酸1 to 17

相关产品

技术指标

Our Abpromise guarantee covers the use of ab38198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

常规信息

  • 别名
    • N/OFQ
    • N23K
    • N23K/N27K
    • Nociceptin, included
    • nocistatin
    • Npnc1
    • OFQ
    • OFQ/N
    • Orphanin FQ
    • Orphanin FQ2
    • Pnoc
    • PNOC_HUMAN
    • ppN/OFQ
    • PPNOC
    • pre-pro-N/OFQ
    • prepronociceptin
    • pronociceptin
    • Propronociceptin
    see all
  • 功能Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
    Nocistatin: Blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia.
    Orphanin FQ2: Has potent analgesic activity.
  • 组织特异性Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation.
  • 序列相似性Belongs to the opioid neuropeptide precursor family.
  • 翻译后修饰Specific enzymatic cleavages at paired basic residues probably yield other active peptides besides nociceptin.
    The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.
  • 细胞定位Secreted.
  • Information by UniProt

Nociceptin peptide (ab38198)参考文献

ab38198 has not yet been referenced specifically in any publications.

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