Anti-Nociceptin抗体(ab100880)

概述

  • 产品名称Anti-Nociceptin抗体
    参阅全部 Nociceptin 一抗
  • 描述
    兔多克隆抗体to Nociceptin
  • 经测试应用适用于: IHC-P, ICCmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Rabbit, Horse, Dog, Pig
  • 免疫原

    Synthetic peptide:

    FGGFTGARKSARKLANQ

    , corresponding to internal sequence amino acids 130-146 of Human Nociceptin

性能

应用

Our Abpromise guarantee covers the use of ab100880 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/2000.
ICC 1/5000.

靶标

  • 功能Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.
    Nocistatin: Blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia.
    Orphanin FQ2: Has potent analgesic activity.
  • 组织特异性Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation.
  • 序列相似性Belongs to the opioid neuropeptide precursor family.
  • 翻译后修饰Specific enzymatic cleavages at paired basic residues probably yield other active peptides besides nociceptin.
    The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • N/OFQ antibody
    • N23K antibody
    • N23K/N27K antibody
    • Nociceptin, included antibody
    • nocistatin antibody
    • Npnc1 antibody
    • OFQ antibody
    • OFQ/N antibody
    • Orphanin FQ antibody
    • Orphanin FQ2 antibody
    • Pnoc antibody
    • PNOC_HUMAN antibody
    • ppN/OFQ antibody
    • PPNOC antibody
    • pre-pro-N/OFQ antibody
    • prepronociceptin antibody
    • pronociceptin antibody
    • Propronociceptin antibody
    see all

Anti-Nociceptin antibody 图像

  • Dual labeling of Nociceptin (green) and enkephalin (red).

Anti-Nociceptin antibody (ab100880)参考文献

ab100880 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab100880.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"