Bioactive fragment of nociceptin. ORL1 (NOP) receptor agonist.
Orphanin FQ (1-7)
生物学描述Bioactive fragment of nociceptin. ORL1 (NOP) receptor agonist. Reduces nociception induced hyperalgesia and displays antinociceptive activity.
存放说明Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
溶解度概述Soluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Katsuyama S et al. Antinociceptive effects of spinally administered nociceptin/orphanin FQ and its N-terminal fragments on capsaicin-induced nociception. Peptides32:1530-5 (2011).
Read more (PubMed: 21672568) »
Kotlinska J & Rafalski P [Nociceptin/orphanin FQ (N/OFQ)--the opioid, antiopioid or neuromodulator?]. Postepy Hig Med Dosw (Online)58:209-15 (2004).
Read more (PubMed: 15114256) »