Anti-NMNAT3抗体(ab121030)

概述

  • 产品名称Anti-NMNAT3抗体
    参阅全部 NMNAT3 一抗
  • 描述
    山羊多克隆抗体to NMNAT3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat
  • 免疫原

    Synthetic peptide:

    C-KALGQGQSVKYLLPE

    , corresponding to internal sequence amino acids 206-220 of Mouse NMNAT3 (NP_653116.1).

  • 阳性对照
    • Mouse heart lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab121030 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).Can be blocked with ab185635.

靶标

  • 功能Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.
  • 组织特异性Expressed in lung and spleen with lower levels in placenta and kidney.
  • 通路Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.
  • 序列相似性Belongs to the eukaryotic NMN adenylyltransferase family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • NaMN adenylyltransferase 3 antibody
    • Nicotinamide mononucleotide adenylyltransferase 3 antibody
    • Nicotinamide nucleotide adenylyltransferase 3 antibody
    • Nicotinate-nucleotide adenylyltransferase 3 antibody
    • NMN adenylyltransferase 3 antibody
    • NMNA3_HUMAN antibody
    • NMNAT 3 antibody
    • Nmnat3 antibody
    • PNAT 3 antibody
    • PNAT-3 antibody
    • PNAT3 antibody
    • Pyridine nucleotide adenylyltransferase 3 antibody
    see all

Anti-NMNAT3 antibody 图像

  • Anti-NMNAT3 antibody (ab121030) at 0.5 µg/ml + Mouse heart lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 28 kDa
    Observed band size : 28 kDa
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

Anti-NMNAT3 antibody (ab121030)参考文献

ab121030 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"