概述

  • 产品名称Anti-NMNAT3抗体
    参阅全部 NMNAT3 一抗
  • 描述
    兔多克隆抗体to NMNAT3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 149-178 of Human NMNAT3 (NP_835471.1).

  • 阳性对照
    • NCI-H460 cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab116288 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 28 kDa.

靶标

  • 功能Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Can also use GTP and ITP as nucleotide donors. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, can use NAD (+), NADH, NAAD, nicotinic acid adenine dinucleotide phosphate (NHD), nicotinamide guanine dinucleotide (NGD) as substrates. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following injury.
  • 组织特异性Expressed in lung and spleen with lower levels in placenta and kidney.
  • 通路Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from nicotinamide D-ribonucleotide: step 1/1.
  • 序列相似性Belongs to the eukaryotic NMN adenylyltransferase family.
  • 细胞定位Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • NaMN adenylyltransferase 3 antibody
    • Nicotinamide mononucleotide adenylyltransferase 3 antibody
    • Nicotinamide nucleotide adenylyltransferase 3 antibody
    • Nicotinate-nucleotide adenylyltransferase 3 antibody
    • NMN adenylyltransferase 3 antibody
    • NMNA3_HUMAN antibody
    • NMNAT 3 antibody
    • Nmnat3 antibody
    • PNAT 3 antibody
    • PNAT-3 antibody
    • PNAT3 antibody
    • Pyridine nucleotide adenylyltransferase 3 antibody
    see all

Anti-NMNAT3 antibody 图像

  • Anti-NMNAT3 antibody (ab116288) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 28 kDa

Anti-NMNAT3 antibody (ab116288)参考文献

ab116288 has not yet been referenced specifically in any publications.

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