概述

  • 产品名称
  • 描述
    兔多克隆抗体to NME3
  • 经测试应用
    适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the center region of human NME3, conjugated to KLH.

  • 阳性对照
    • CEM cell lysate; Paraffin embedded human breast carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab71502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
IHC-P 1/50 - 1/100.
ELISA 1/1000.

靶标

  • 功能
    Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
  • 序列相似性
    Belongs to the NDK family.
  • 发展阶段
    Preferentially expressed at early stages of myeloid differentiation of highly purified CD34+ cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • c371H6.2 antibody
    • DR-nm23 antibody
    • Expressed in non metastatic cells 3 antibody
    • NDK 3 antibody
    • NDK3 antibody
    • NDK3_HUMAN antibody
    • NDP kinase 3 antibody
    • NDP kinase C antibody
    • NDPK C antibody
    • NDPKC antibody
    • NM23 H3 antibody
    • nm23-H3 antibody
    • NM23H3 antibody
    • NME 3 antibody
    • NME/NM23 nucleoside diphosphate kinase 3 antibody
    • Nme3 antibody
    • Non metastatic cells 3 protein expressed in antibody
    • Nucleoside diphosphate kinase 3 antibody
    • Nucleoside diphosphate kinase C antibody
    see all

图片

  • Anti-NME3 antibody (ab71502) at 1/40 dilution + CEM cell lysate at 35 µg

    Predicted band size : 19 kDa
    Observed band size : 19 kDa
    Additional bands at : 32 kDa,50 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemical analysis of paraffin embedded human breast carcinoma tissue using ab71502 at 1/50 dilution.

文献

ab71502 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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