概述

  • 产品名称Anti-NMDAR2C (phospho S1096)抗体
    参阅全部 NMDAR2C 一抗
  • 描述
    兔多克隆抗体to NMDAR2C (phospho S1096)
  • 特异性Specific for the NR2C subunit of the NMDA receptor phosphorylated at Ser1096. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide that was used to generate the antibody but not by the corresponding dephospho-peptide.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat
    预测可用于: Cow, Dog, Human, Non Human Primates
  • 免疫原

    Synthetic peptide corresponding to Rat NMDAR2C (C terminal) (phospho S1096).
    Database link: Q00961

  • 阳性对照
    • Mouse brain lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: None
    Constituents: 50% Glycerol, 100µg/ml BSA, 150 mM Sodium chloride, 10mM HEPES, pH 7.5
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106569 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 135 kDa.

靶标

  • 功能NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • 组织特异性Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
  • 序列相似性Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily.
  • 细胞定位Cell membrane. Cell junction, synapse, postsynaptic cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GluN2C antibody
    • Glutamate [NMDA] receptor subunit epsilon-3 antibody
    • Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody
    • Glutamate receptor ionotropic, NMDA 2C antibody
    • Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody
    • Grin2c antibody
    • N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody
    • N Methyl D Aspartate Receptor Subtype 2C antibody
    • N methyl D aspartate receptor subunit 2C antibody
    • N-methyl D-aspartate receptor subtype 2C antibody
    • NMDAR2C antibody
    • NMDE3_HUMAN antibody
    • NR2C antibody
    • OTTHUMP00000041930 antibody
    see all

Anti-NMDAR2C (phospho S1096) antibody 图像

  • All lanes : Anti-NMDAR2C (phospho S1096) antibody (ab106569) at 1/1000 dilution

    Lane 1 : Mouse brain lysate
    Lane 2 : Mouse brain lysate with immunoreactivity blocked by preadsorption with the phospho-peptide


    Predicted band size : 135 kDa

Anti-NMDAR2C (phospho S1096) antibody (ab106569)参考文献

This product has been referenced in:
  • Chen BS & Roche KW Growth factor-dependent trafficking of cerebellar NMDA receptors via protein kinase B/Akt phosphorylation of NR2C. Neuron 62:471-8 (2009). Read more (PubMed: 19477150) »

See 1 Publication for this product

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