概述

  • 产品名称
  • 描述
    兔多克隆抗体to NM23A
  • 特异性
    ab55417 detects endogenous levels of total NM23A protein.
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from human NM23A.

  • 阳性对照
    • K562 cell extract.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab55417 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 17 kDa (predicted molecular weight: 17 kDa).
ELISA 1/5000.

靶标

  • 功能
    Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
  • 组织特异性
    Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation. Isoform 3 is ubiquitously expressed.
  • 序列相似性
    Belongs to the NDK family.
  • 细胞定位
    Cytoplasm. Nucleus. Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AWD antibody
    • AWD, drosophila, homolog of antibody
    • GAAD antibody
    • Granzyme A activated DNase antibody
    • Granzyme A-activated DNase antibody
    • GZMA activated DNase antibody
    • Metastasis inhibition factor NM23 antibody
    • NB antibody
    • NBS antibody
    • NDK A antibody
    • NDKA antibody
    • NDKA_HUMAN antibody
    • NDP kinase A antibody
    • NDPK-A antibody
    • NDPKA antibody
    • NM23 antibody
    • NM23 long variant, included antibody
    • nm23-H1 antibody
    • NM23-M1 antibody
    • NM23H1B, included antibody
    • NME/NM23 nucleoside diphosphate kinase 1 antibody
    • Nme1 antibody
    • NME1-NME2 spliced read-through transcript, included antibody
    • Non-metastatic cells 1, protein (NM23A) expressed in antibody
    • Nonmetastatic cells 1, protein expressed in antibody
    • Nonmetastatic protein 23 antibody
    • Nonmetastatic protein 23, homolog 1 antibody
    • Nucleoside diphosphate kinase A antibody
    • Tumor metastatic process-associated protein antibody
    see all

图片

  • All lanes : Anti-NM23A antibody (ab55417) at 1/500 dilution

    Lane 1 : K562 cell extract, without immunizing peptide
    Lane 2 : K562 cell extract, with immunizing peptide


    Predicted band size : 17 kDa
    Observed band size : 17 kDa

实验方案

文献

This product has been referenced in:
  • Li L  et al. Serotonin(1A)-receptor-dependent signaling proteins in mouse hippocampus. Neuropharmacology 57:556-66 (2009). WB ; Mouse . Read more (PubMed: 19607848) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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