概述

  • 产品名称Anti-NLRX1抗体
    参阅全部 NLRX1 一抗
  • 描述
    山羊多克隆抗体to NLRX1
  • 特异性ab106756 is expected to recognize both reported isoforms (NP_078894.2; NP_733840.1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    C-NFSGETLDSTDPSN

    , corresponding to internal sequence amino acids 405-419 of Human NLRX1 (NP_078894.2; NP_733840.1).

  • 阳性对照
    • Human Breast cancer lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 100 kDa (predicted molecular weight: 108 kDa).

靶标

  • 功能Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (PubMed:18219313).
  • 组织特异性Ubiquitously expressed. Strongest expression in mammary gland, heart and muscle. Detected in HELA, 293T, THP-1, HL60, RAJI, and JURKAT cell lines (at protein level).
  • 序列相似性Belongs to the NLRP family.
    Contains 7 LRR (leucine-rich) repeats.
    Contains 1 NACHT domain.
  • 细胞定位Mitochondrion outer membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Caterpiller protein 11.3 antibody
    • CLR11.3 antibody
    • DLNB26 antibody
    • FLJ21478 antibody
    • MGC131937 antibody
    • MGC21025 antibody
    • NLR family member X1 antibody
    • NLR family, X1 antibody
    • Nlrx1 antibody
    • NLRX1_HUMAN antibody
    • NOD-like receptor X1 antibody
    • NOD26 antibody
    • NOD5 antibody
    • NOD9 antibody
    • Nucleotide-binding oligomerization domain protein 26 antibody
    • Nucleotide-binding oligomerization domain protein 5 antibody
    • Nucleotide-binding oligomerization domain protein 9 antibody
    • nucleotide-binding oligomerization domain, leucine rich repeat containing X1 antibody
    • Protein Caterpiller 11.3 antibody
    see all

Anti-NLRX1 antibody 图像

  • Anti-NLRX1 antibody (ab106756) at 2 µg/ml + Human Breast cancer lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 108 kDa

Anti-NLRX1 antibody (ab106756)参考文献

ab106756 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab106756.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"