参阅全部 NLRP7 一抗
- 特异性At least four isoforms of NLRP7 are known to exist; this antibody will recognize all of them. This antibody is predicted to not cross-react with other NLRP family members.
IHC-P, ICC/IF, WBmore details
Synthetic peptide corresponding to Human NLRP7 (N terminal).
Database link: Q8WX94
- Human brain tissue lysate, K562 cell lysate
- 存放说明Shipped at 4°C. Store at +4°C.
- 存储溶液Preservative: 0.02% Sodium Azide
Concentration information loading...
- 纯度Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 10 µg/ml.
||Use a concentration of 20 µg/ml.
||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 112 kDa.
- 功能Inhibits CASP1/caspase-1-dependent IL1B secretion.
- 组织特异性Expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. Not detected in skeletal muscle.
- 疾病相关Defects in NLRP7 are the cause of hydatidiform mole (HYDM) [MIM:231090]. HYDM is an abnormal human pregnancy with no embryo and cystic degeneration of placental villi.
- 序列相似性Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 NACHT domain.
Information by UniProt
- CLR19.4 antibody
- FLJ94610 antibody
- HYDM antibody
Anti-NLRP7 antibody (ab105405)参考文献
has not yet been referenced specifically in any publications.
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