At least two isoforms of NLRP10 are known to exist; this antibody will recognize both. The antibody is predicted to not cross-react with other NLRP family members.
A 14 amino acid peptide from near the N terminus of Human NLRP10 (NP_789791).
- Human brain tissue lysate
Shipped at 4°C. Store at +4°C.
Preservative: 0.02% Sodium Azide
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use at an assay dependent concentration.
||Use a concentration of 20 µg/ml.
||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 75 kDa.
Inhibits CASP1/caspase-1-dependent IL1B secretion and PYCARD-mediated apoptosis, but not that induced by FAS or BID.
Widely expressed with highest levels in heart, brain and skeletal muscle.
Belongs to the NLRP family.
Contains 1 DAPIN domain.
Contains 1 NACHT domain.
Information by UniProt
- CLR11.1 antibody
- NACHT, leucine rich repeat and PYD containing 10 antibody
- NACHT, LRR and PYD domains containing protein 10 antibody
has not yet been referenced specifically in any publications.
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