The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 204 kDa.
Use at an assay dependent concentration.
Use a concentration of 5 µg/ml.
功能Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
组织特异性Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
序列相似性Belongs to the NLRP family. Contains 26 LRR (leucine-rich) repeats. Contains 1 NACHT domain.