概述

  • 产品名称Anti-NLGN4X抗体
    参阅全部 NLGN4X 一抗
  • 描述
    小鼠单克隆抗体to NLGN4X
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: RVRDHYRATK VAFWLELVPH LHNLNEIFQY VSTTTKVPPP DMTSFPYGTR RSPAKIWPTT KRPAITPANN PKHSKDPHKT GPEDTTVLIE TKRDYSTELS , corresponding to amino acids 577-677 of Human Neuroligin 4

性能

应用

Our Abpromise guarantee covers the use of ab57466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Putative neuronal cell surface protein involved in cell-cell-interactions.
    • 组织特异性Expressed at highest levels in heart. Expressed at lower levels in liver, skeletal muscle and pancreas and at very low levels in brain.
    • 疾病相关Defects in NLGN4X may be the cause of susceptibility to autism X-linked type 2 (AUTSX2) [MIM:300495]. AUTSX2 is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.
      Defects in NLGN4X may be the cause of susceptibility to X-linked Asperger syndrome 2 (ASPGX2) [MIM:300497]. ASPGX2 is considered to be a form of childhood autism.
    • 序列相似性Belongs to the type-B carboxylesterase/lipase family.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ASPGX2 antibody
      • AUTSX2 antibody
      • HLNX antibody
      • HNL4X antibody
      • HNLX antibody
      • KIAA1260 antibody
      • neuroligin 4, X-linked antibody
      • Neuroligin X antibody
      • Neuroligin-4 antibody
      • NL4 antibody
      • NLGN antibody
      • NLGN4 antibody
      • NLGN4X antibody
      • NLGNX_HUMAN antibody
      • OTTHUMP00000022863 antibody
      • OTTHUMP00000022864 antibody
      • OTTHUMP00000022865 antibody
      • X-linked antibody
      see all

    Anti-NLGN4X antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57466 Neuroligin 4 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-NLGN4X antibody (ab57466)参考文献

    ab57466 has not yet been referenced specifically in any publications.

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