概述

  • 产品名称
  • 描述
    兔多克隆抗体to Nkx3.1
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Rat, Guinea pig, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal residues 180 - 229 (KRKQLSSELG DLEKHSSLPA LKEEAFSRAS LVSVYNSYPY YPYLYCVGSW) of Human Nkx3.1 (NP_006158)

  • 阳性对照
    • 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab83973 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
  • 组织特异性
    Highly expressed in the prostate and, at a lower level, in the testis.
  • 序列相似性
    Belongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 翻译后修饰
    Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BAPX 2 antibody
    • BAPX2 antibody
    • Homeobox protein NK-3 homolog A antibody
    • Homeobox protein Nkx 3.1 antibody
    • Homeobox protein Nkx-3.1 antibody
    • Homeobox protein Nkx3.1 antibody
    • NK homeobox (Drosophila) family 3 A antibody
    • NK homeobox family 3 A antibody
    • NK homeobox, family 3, member A antibody
    • NK3 homeobox 1 antibody
    • NK3 transcription factor homolog A antibody
    • NK3 transcription factor related locus 1 antibody
    • NKX 3 antibody
    • Nkx 3.1 antibody
    • NKX 3A antibody
    • NKX3 1 antibody
    • NKX3 antibody
    • Nkx3-1 antibody
    • NKX3.1 antibody
    • Nkx3.1, mouse, homolog of antibody
    • NKX31_HUMAN antibody
    • NKX3A antibody
    see all

Anti-Nkx3.1 antibody 图像

  • Anti-Nkx3.1 antibody (ab83973) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 26 kDa
    Observed band size : 32 kDa (why is the actual band size different from the predicted?)

实验方案

Anti-Nkx3.1 antibody (ab83973)参考文献

ab83973 has not yet been referenced specifically in any publications.

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