概述

  • 产品名称Anti-Nkx3.1抗体
    参阅全部 Nkx3.1 一抗
  • 描述
    兔多克隆抗体to Nkx3.1
  • 特异性ab58382 detects endogenous levels of total Nkx3.1 protein.
  • 经测试应用适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from N terminal residues of human Nkx3.1.

  • 阳性对照
    • Human breast carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab58382 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ELISA 1/20000.

靶标

  • 功能Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
  • 组织特异性Highly expressed in the prostate and, at a lower level, in the testis.
  • 序列相似性Belongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 翻译后修饰Ubiquitinated by TOPORS; monoubiquitinated at several residues and also polyubiquitinated on single residues.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BAPX 2 antibody
    • BAPX2 antibody
    • Homeobox protein NK-3 homolog A antibody
    • Homeobox protein Nkx 3.1 antibody
    • Homeobox protein Nkx-3.1 antibody
    • Homeobox protein Nkx3.1 antibody
    • NK homeobox (Drosophila) family 3 A antibody
    • NK homeobox family 3 A antibody
    • NK homeobox, family 3, member A antibody
    • NK3 homeobox 1 antibody
    • NK3 transcription factor homolog A antibody
    • NK3 transcription factor related locus 1 antibody
    • NKX 3 antibody
    • Nkx 3.1 antibody
    • NKX 3A antibody
    • NKX3 1 antibody
    • NKX3 antibody
    • Nkx3-1 antibody
    • NKX3.1 antibody
    • Nkx3.1, mouse, homolog of antibody
    • NKX31_HUMAN antibody
    • NKX3A antibody
    see all

Anti-Nkx3.1 antibody 图像

  • ab58382 at 1/50 dilution staining Nkx3.1 in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunising peptide.

Anti-Nkx3.1 antibody (ab58382)参考文献

ab58382 has not yet been referenced specifically in any publications.

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