概述

  • 产品名称Anti-NKIRAS2抗体
    参阅全部 NKIRAS2 一抗
  • 描述
    小鼠单克隆抗体to NKIRAS2
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-192 of Human NKIRAS2

性能

应用

Our Abpromise guarantee covers the use of ab57303 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
    • 组织特异性Widely expressed.
    • 序列相似性Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
    • 结构域In contrast to other members of the Ras family, the members of the KappaB-Ras subfamily do not contain the conserved Gly and Gln residues in positions 13 and 65, which are replaced by Ala and Leu residues, respectively, and are therefore similar to the constitutively active forms of oncogenic forms of Ras. This suggests that members of this family are clearly different from other small GTPases proteins.
    • 细胞定位Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZP434N1526 antibody
      • I kappa B interacting Ras like protein 2 antibody
      • I-kappa-B-interacting Ras-like protein 2 antibody
      • Kappa B Ras protein 2 antibody
      • Kappa B-Ras protein 2 antibody
      • KappaB Ras2 antibody
      • KappaB-Ras2 antibody
      • KBRAS 2 antibody
      • KBRAS2 antibody
      • KBRS2_HUMAN antibody
      • MGC74742 antibody
      • NF kappa B inhibitor interacting Ras like protein 2 antibody
      • NF-kappa-B inhibitor-interacting Ras-like protein 2 antibody
      • NFKB inhibitor interacting Ras like 2 antibody
      • NFKB inhibitor interacting Ras like protein 2 antibody
      • NKIRAS 2 antibody
      • NKIRAS2 antibody
      see all

    Anti-NKIRAS2 antibody 图像

    • NKIRAS2 antibody (ab57303) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human tonsil.


    • Predicted band size : 22 kDa
      NKIRAS2 antibody (ab57303) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-NKIRAS2 antibody (ab57303)参考文献

    ab57303 has not yet been referenced specifically in any publications.

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