Anti-NKG2D抗体[MM0489-10R27] (ab89807)

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概述

  • 产品名称
    Anti-NKG2D抗体[MM0489-10R27]
    参阅全部 NKG2D 一抗
  • 描述
    小鼠单克隆抗体[MM0489-10R27] to NKG2D
  • 宿主
    Mouse
  • 经测试应用
    适用于: WB, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment to extracellular domain of Human NKG2D

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and filtered through a 0.2 µm filter.
  • 克隆
    单克隆
  • 克隆编号
    MM0489-10R27
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 25 kDa.
Flow Cyt 1/50 - 1/100.

ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

靶标

  • 功能
    Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
  • 组织特异性
    Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
  • 序列相似性
    Contains 1 C-type lectin domain.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
    • 别名
      • CD314 antibody
      • CD314 antigen antibody
      • D12S2489E antibody
      • Killer cell lectin like receptor subfamily K member 1 antibody
      • Killer cell lectin-like receptor subfamily K member 1 antibody
      • KLR antibody
      • KLRC4 KLRK1 readthrough antibody
      • KLRK1 antibody
      • NK cell receptor D antibody
      • NK lectin-like receptor antibody
      • NKG2 D activating NK receptor antibody
      • NKG2 D type II integral membrane protein antibody
      • NKG2-D antibody
      • NKG2-D type II integral membrane protein antibody
      • NKG2-D-activating NK receptor antibody
      • Nkg2d antibody
      • NKG2D_HUMAN antibody
      • NKLLR antibody
      • NKR P2 antibody
      • Nkrp2 antibody
      see all

    图片

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NKG2D antibody [MM0489-10R27] (ab89807)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NKG2D antibody [MM0489-10R27] (ab89807)

      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling NKG2D with ab89807. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

    文献

    ab89807 has not yet been referenced specifically in any publications.

    发表研究结果有使用 ab89807？请让我们知道，以便我们可以引用本数据表中的参考文章。

    客户评价及客户问答

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    1 Review or Q&A

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    Votes: Highest First

    Inquiry: Hi, I am looking for a conjugated mouse anti-human NKG2D IgG1 antibody that does not block the interaction of NKG2D with its ligands. I understand that the anti-mouse clone A10 fulfills this in mice but sadly that is of no help! Ideally, it wo...

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    Thank you for contacting us.


    I contacted the laboratory in order to answer your questions. I can confirm that for the Anti-NKG2D antibody [MM0489-10R27] (ab89807) regrettably it is not known if it would block the interactions of NKG2D wit...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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