Anti-Nitrotyrosine抗体[EM-30] (ab125106)

概述

  • 产品名称
    Anti-Nitrotyrosine抗体[EM-30]
    参阅全部 Nitrotyrosine 一抗
  • 描述
    小鼠单克隆抗体[EM-30] to Nitrotyrosine
  • 经测试应用
    适用于: WB, IHC-P, IHC-Frmore details
  • 免疫原

    Chemical/ Small Molecule corresponding to Nitrotyrosine.

  • 阳性对照
    • NO2-BSA, NO2-HSA; Human colon cancer epithelium and prostate hyperplasia tissues.

性能

应用

Our Abpromise guarantee covers the use of ab125106 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration.
IHC-P Use a concentration of 10 µg/ml.
IHC-Fr Use a concentration of 10 µg/ml.

靶标

  • 相关性
    The cellular production of highly reactive nitrogen species derived from nitric oxide, such as peroxynitrite, nitrogen dioxide and nitryl chloride, leads to the nitration of tyrosine resides in tissue proteins. The extent of protein nitrotyrosine formation provides an index of the production of reactive nitrogen species and potential cell damage over a period of time. Nitrotyrosine can be measured by amino-acid analysis of protein hydrolysates and detected, estimated semi-quantitatively and located in cells and tissues by immunocytochemical techniques using antibodies directed against the nitrotyrosine hapten.

图片

  • Immunohistochemical analysis of Human tumoral colon epithelium (frozen sections) labelling Nitrotyrosine with ab125106 at 10 µg/mL. 

文献

ab125106 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your reply.

To confirm, the epitope for this antibody is not species specific. In theory, it should detect Nitrotyrosine in all species. However, I have collected the following information for you:

ab125106 Anti-Nitr...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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