Anti-Nitro tyrosine抗体(FITC) (ab27647)

概述

  • 产品名称Anti-Nitro tyrosine抗体(FITC)
    参阅全部 Nitro tyrosine 一抗
  • 描述
    山羊多克隆抗体to Nitro tyrosine (FITC)
  • 偶联物FITC. Ex: 493nm, Em: 528nm
  • 特异性Specifically binds to nitrated proteins. Molar F/P ratio is 4.6.
  • 经测试应用适用于: ICC/IFmore details
  • 免疫原

    Chemical/ Small Molecule (Nitrtyrosine modified protein)

性能

应用

Our Abpromise guarantee covers the use of ab27647 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent dilution.

靶标

  • 相关性Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
  • 别名
    • NO tyrosine antibody
    • nTyr antibody

Anti-Nitro tyrosine antibody (FITC) (ab27647)参考文献

ab27647 has not yet been referenced specifically in any publications.

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Thank you for contacting Abcam.

To our knowledge, ab27647 has not been tested in IHC, it has only been tested in ICC/IF, therefore we cannot guarantee that it willwork inthisapplication, so it is not covered under our Abpromise.

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