Anti-Nitrotyrosine抗体(ab42789)
Key features and details
- Rabbit polyclonal to Nitrotyrosine
- Suitable for: WB, ELISA, IHC-FoFr, IHC-P
- Isotype: IgG
概述
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产品名称
Anti-Nitrotyrosine抗体
参阅全部 Nitrotyrosine 一抗 -
描述
兔多克隆抗体to Nitrotyrosine -
宿主
Rabbit -
特异性
This antibody reacts with free and bound nitrotyrosine. There is no cross reaction with free or bound tyrosine -
经测试应用
适用于: WB, ELISA, IHC-FoFr, IHC-Pmore details -
种属反应性
not applicable -
免疫原
Chemical/ Small Molecule corresponding to Nitrotyrosine conjugated to keyhole limpet haemocyanin.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab42789于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
Use at an assay dependent concentration.
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ELISA |
Use at an assay dependent concentration.
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IHC-FoFr |
Use at an assay dependent concentration. PubMed: 22540017
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IHC-P |
Use at an assay dependent concentration. PubMed: 24551153
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说明 |
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WB
Use at an assay dependent concentration. |
ELISA
Use at an assay dependent concentration. |
IHC-FoFr
Use at an assay dependent concentration. PubMed: 22540017 |
IHC-P
Use at an assay dependent concentration. PubMed: 24551153 |
靶标
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相关性
The cellular production of highly reactive nitrogen species derived from nitric oxide, such as peroxynitrite, nitrogen dioxide and nitryl chloride, leads to the nitration of tyrosine resides in tissue proteins. The extent of protein nitrotyrosine formation provides an index of the production of reactive nitrogen species and potential cell damage over a period of time. Nitrotyrosine can be measured by amino-acid analysis of protein hydrolysates and detected, estimated semi-quantitatively and located in cells and tissues by immunocytochemical techniques using antibodies directed against the nitrotyrosine hapten.
数据表及文件
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Datasheet download
文献 (21)
ab42789 被引用在 21 文献中.
- Wang Y et al. Slow flow induces endothelial dysfunction by regulating thioredoxin-interacting protein-mediated oxidative metabolism and vascular inflammation. Front Cardiovasc Med 9:1064375 (2022). PubMed: 36465470
- Patel B et al. Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain. Mol Metab 43:101123 (2021). PubMed: 33227495
- Török M et al. Network analysis of the left anterior descending coronary arteries in swim-trained rats by an in situ video microscopic technique. Biol Sex Differ 12:37 (2021). PubMed: 34039432
- Musicki B et al. TSPO ligand FGIN-1-27 controls priapism in sickle cell mice via endogenous testosterone production. J Cell Physiol 236:3073-3082 (2021). PubMed: 32974910
- Ryan BJ et al. REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model. J Neurosci 41:3731-3746 (2021). PubMed: 33563726