Anti-Nitro tyrosine抗体(ab24497)

概述

  • 产品名称Anti-Nitro tyrosine抗体
    参阅全部 Nitro tyrosine 一抗
  • 描述
    小鼠单克隆抗体to Nitro tyrosine
  • 特异性ab24497 recognises Nitrotyrosine containing proteins.
  • 经测试应用适用于: WBmore details
  • 免疫原

    Peroxynitrite treated KLH

性能

应用

Our Abpromise guarantee covers the use of ab24497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 2 µg/ml.

靶标

  • 相关性Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
  • 别名
    • NO tyrosine antibody
    • nTyr antibody

Anti-Nitro tyrosine antibody (ab24497)参考文献

ab24497 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. A useful positive control for this antibody is protein extracted from human A431 cells (Human epithelial carcinoma cell line) or other cells pretreated with peroxynitrite for 5 min. In the following publication, they u...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"