概述

  • 产品名称
    Anti-Nitro tyrosine抗体
    参阅全部 Nitro tyrosine 一抗
  • 描述
    兔多克隆抗体to Nitro tyrosine
  • 特异性
    This antibody reacts against Nitrotyrosine, but with less than 10% reactivity against chlorotyrosine.
  • 经测试应用
    适用于: WBmore details
  • 免疫原

    Nitrotyrosine containing synthetic peptide.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, Tris buffered saline, 0.5mg/ml BSA, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 纯化说明
    This antibody was prepared by affinity purification to exclude non nitrotyrosine antibodies generated against the antigenic peptide backbone.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23704 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 µg/ml.

靶标

  • 相关性
    Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
  • 别名
    • NO tyrosine antibody
    • nTyr antibody

实验方案

Anti-Nitro tyrosine antibody (ab23704)参考文献

This product has been referenced in:
  • Zager RA  et al. Acute renal failure: determinants and characteristics of the injury-induced hyperinflammatory response. Am J Physiol Renal Physiol 291:F546-56 (2006). WB ; Mouse . Read more (PubMed: 16638912) »

See 1 Publication for this product

Product Wall

Thank you again for your patience. Yes, this is correct. The result will vary based upon the sample. Any nitrosylated protein will be detected and the results will vary based on the size of the sample protein. The result you have observed is indee...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册