Anti-Nitro tyrosine抗体(ab20117)

概述

  • 产品名称
    Anti-Nitro tyrosine抗体
    参阅全部 Nitro tyrosine 一抗
  • 描述
    山羊多克隆抗体to Nitro tyrosine
  • 特异性
    Specifically binds to nitro-LDL and other nitrated proteins.
  • 经测试应用
    适用于: WB, ELISAmore details
  • 免疫原

    Pure nitrated Keyhole Limpet Hemocyanin (NY-KLH).

性能

应用

Our Abpromise guarantee covers the use of ab20117 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    ELISA: 1/20000 - 1/160000. WB: 1/20000 - 1/160000. Dilution optimised using Chromogenic detection. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性
      Nitric oxide (NO) is a product of the enzymatic conversion of arginine to citrulline by nitric oxide synthase. NO reacts rapidly with superoxide to form peroxynitrite. At physiological pH and in the presence of transition metals, peroxynitrite undergoes heterolytic cleavage to form hydroxyl anion and nitronium ion, the latter of which nitrates protein tyrosine residues. Thus, the presence of nitrotyrosine on proteins can be used as a marker for peroxynitrite formation in vivo. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic placques.
    • 别名
      • NO tyrosine antibody
      • nTyr antibody

    实验方案

    文献

    ab20117 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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