概述

  • 产品名称Anti-NIT1抗体
    参阅全部 NIT1 一抗
  • 描述
    兔多克隆抗体to NIT1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N-terminal amino acids 71-120 (

    VREAARLGACLAFLPEAFDFIARDPAETLHLSEPLGGKLLEEYTQLAREC

    ) of Human NIT1 (NP_005591).

  • 阳性对照
    • 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab98066 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 36 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
  • 组织特异性Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.
  • 序列相似性Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
    Contains 1 CN hydrolase domain.
  • 细胞定位Cytoplasm. Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC57670 antibody
    • NIT1 antibody
    • NIT1_HUMAN antibody
    • Nitrilase 1 antibody
    • Nitrilase homolog 1 antibody
    see all

Anti-NIT1 antibody 图像

  • Anti-NIT1 antibody (ab98066) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T Cell Lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 36 kDa

Anti-NIT1 antibody (ab98066)参考文献

ab98066 has not yet been referenced specifically in any publications.

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