概述
- 产品名称Anti-NIR1抗体
参阅全部 NIR1 一抗 - 描述山羊多克隆抗体to NIR1
- 经测试应用适用于: ELISA, IHC-Pmore details
- 种属反应性与反应: Human
预测可用于: Mouse
- 免疫原
Synthetic peptide:
SWARGPPKFESVP
, corresponding to C terminal amino acids 962-974 of Human NIR1 (UniProt ID: Q9BZ71). - 阳性对照
- Human brain cortex
性能
- 形式Liquid
- 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
- 存储溶液pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... - 纯度Immunogen affinity purified
- 克隆多克隆
- 同种型IgG
- 研究领域
相关产品
- Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab115593 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| ELISA | 1/16000. | |
| IHC-P | Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
- 功能Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity). Binds calcium ions.
- 组织特异性Detected in brain and spleen, and at low levels in ovary.
- 疾病相关Defects in PITPNM3 are the cause of cone-rod dystrophy type 5 (CORD5) [MIM:600977]. CORDs are inherited retinal dystrophies belonging to the group of pigmentary retinopathies. CORDs are characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
- 序列相似性Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
Contains 1 DDHD domain. - 细胞定位Endomembrane system.
- Information by UniProt
-
数据库链接
- Entrez Gene: 83394 Human
- Entrez Gene: 327958 Mouse
- Omim: 608921 Human
- SwissProt: Q9BZ71 Human
- SwissProt: Q3UHE1 Mouse
- Unigene: 183983 Human
- Unigene: 351793 Mouse
-
别名
- CORD5 antibody
- Membrane associated phosphatidylinositol transfer protein 3 antibody
- membrane-associated 3 antibody
see all
Anti-NIR1 antibody 图像
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-NIR1 antibody (ab115593)ab115593, at 5 µg/ml, staining NIR1 in formalin fixed, paraffin embedded Human brain, cortex by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated anti-goat secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Anti-NIR1 antibody (ab115593)参考文献
ab115593 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"