概述

  • 产品名称Anti-NIPSNAP1抗体
    参阅全部 NIPSNAP1 一抗
  • 描述
    兔多克隆抗体to NIPSNAP1
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    a 19 amino acid synthetic peptide from near the center of human NIPSNAP.

  • 阳性对照
    • human brain tissue lysate

性能

应用

Our Abpromise guarantee covers the use of ab67324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use a concentration of 2.5 µg/ml.

靶标

  • 相关性NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.
  • 细胞定位Mitochondrial
  • 数据库链接
  • 别名
    • NIPSNAP 1 antibody
    • Nipsnap homolog 1 (C. elegans) antibody
    • Protein NipSnap homolog 1 antibody

Anti-NIPSNAP1 antibody 图像

  • Immunofluorescence of NIPSNAP1 in Human brain tissue with ab67324 at 20 ug/mL.

  • Lane 1 : Anti-NIPSNAP1 antibody (ab67324) at 0.5 µg/ml
    Lane 2 : Anti-NIPSNAP1 antibody (ab67324) at 1 µg/ml

    Lane 1 : human brain tissue lysate
    Lane 2 : human brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 33 kDa
    Observed band size : 33 kDa
  • ab67324 at 2.5 µg/ml staining NIPSNAP1 in human prostate tissue section by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded sections).

Anti-NIPSNAP1 antibody (ab67324)参考文献

ab67324 has not yet been referenced specifically in any publications.

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