Anti-Nicotinic Acetylcholine Receptor beta 3抗体(ab77393)

概述

  • 产品名称Anti-Nicotinic Acetylcholine Receptor beta 3抗体
    参阅全部 Nicotinic Acetylcholine Receptor beta 3 一抗
  • 描述
    山羊多克隆抗体to Nicotinic Acetylcholine Receptor beta 3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Xenopus laevis, Chimpanzee, Zebrafish
  • 免疫原

    Synthetic peptide:

    SRHVKKEHFISQ

    , corresponding to internal sequence amino acids 403-414 of Human Nicotinic Acetylcholine Receptor beta 3

  • 阳性对照
    • Human Cerebellum lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab77393 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1/16,000.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.
    • 细胞定位Cell Membrane
    • 数据库链接
    • 别名
      • AChR antibody
      • Beta-3 subunit precursor antibody
      • CHRNB3 antibody
      • Neuronal acetylcholine receptor protein antibody

    Anti-Nicotinic Acetylcholine Receptor beta 3 antibody 图像

    • Anti-Nicotinic Acetylcholine Receptor beta 3 antibody (ab77393) at 1 µg/ml + Human Cerebellum lysate (in RIPA buffer) at 35 µg
      Developed using the ECL technique

      Predicted band size : 51 kDa
      Observed band size : 51 kDa

    Anti-Nicotinic Acetylcholine Receptor beta 3 antibody (ab77393)参考文献

    ab77393 has not yet been referenced specifically in any publications.

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