Anti-Nicotinic Acetylcholine Receptor beta 2抗体[270] (ab24698)


  • 产品名称Anti-Nicotinic Acetylcholine Receptor beta 2抗体[270]
    参阅全部 Nicotinic Acetylcholine Receptor beta 2 一抗
  • 描述
    大鼠单克隆抗体[270] to Nicotinic Acetylcholine Receptor beta 2
  • 经测试应用适用于: IP, WB, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Chicken
  • 免疫原

    Purified neuronal Nicotinic Acetylcholine Receptors from chicken brain.

  • 表位This clone binds to the extracellular surface of neuronal Acetylcholine Receptor beta 2-subunits.
  • 常规说明

    This antibody binds to native subunits as well as denatured subunits although with lower affinity. Clone 270 is useful for immunoisolating and pharmacologically characterizing AChRs, immunopurification of AChRs, and is also useful histologically.



Our Abpromise guarantee covers the use of ab24698 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP 1/150.
WB 1/1000. Predicted molecular weight: 57 kDa.
ICC/IF Use at an assay dependent dilution. PubMed: 19176801


  • 功能After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 疾病相关Defects in CHRNB2 are the cause of nocturnal frontal lobe epilepsy type 3 (ENFL3) [MIM:605375]. ENFL3 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-2/CHRNB2 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acetylcholine receptor beta 2 neural antibody
    • ACHB2_HUMAN antibody
    • ACHN antibody
    • AChR antibody
    • Acrb 2 antibody
    • Acrb2 antibody
    • b2 nAchR antibody
    • Cholinergic receptor nicotinic beta 2 antibody
    • Cholinergic receptor nicotinic beta polypeptide 2 antibody
    • Cholinergic receptor nicotinic beta polypeptide 2 neuronal antibody
    • cholinergic receptor, nicotinic, beta 2 (neuronal) antibody
    • Chrnb2 antibody
    • EFNL 3 antibody
    • EFNL3 antibody
    • nAChRB2 antibody
    • Neuronal acetylcholine receptor protein beta 2 chain precursor antibody
    • Neuronal acetylcholine receptor protein subunit beta 2 antibody
    • Neuronal acetylcholine receptor subunit beta-2 antibody
    • Neuronal nicotinic acetylcholine receptor beta 2 antibody
    see all

Anti-Nicotinic Acetylcholine Receptor beta 2 antibody [270] (ab24698)参考文献

This product has been referenced in:
  • Liu Q  et al. A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptides. J Neurosci 29:918-29 (2009). ICC/IF ; Xenopus laevis . Read more (PubMed: 19176801) »

See 1 Publication for this product

Product Wall

Thank you for your enquiry. We do not have a recommended positive control for this antiserum. However, given that this antiserum recognizes Nicotinic Acetylcholine Receptor I would recommend rat brain lysate for use as a positive control for wester...

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