Anti-Nicotinic Acetylcholine Receptor alpha 7抗体(ab110851)

概述

性能

应用

Our Abpromise guarantee covers the use of ab110851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 3 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-7/CHRNA7 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 7nAChR antibody
    • a7 nicotinic acetylcholine receptor antibody
    • acetylcholine receptor, neuronal nicotinic, alpha-7 subunit antibody
    • ACHA7_HUMAN antibody
    • AChR antibody
    • Acra7 antibody
    • alpha 7 neuronal nicotinic acetylcholine receptor antibody
    • alpha-7 nicotinic cholinergic receptor subunit antibody
    • alpha7 antibody
    • cholinergic receptor, neuronal nicotinic, alpha polypeptide 7 antibody
    • cholinergic receptor, nicotinic, alpha 7 (neuronal) antibody
    • cholinergic receptor, nicotinic, alpha 7 antibody
    • cholinergic receptor, nicotinic, alpha polypeptide 7 antibody
    • CHRNA7 antibody
    • CHRNA7-2 antibody
    • NACHRA7 antibody
    • neuronal acetylcholine receptor protein, alpha-7 chain antibody
    • Neuronal acetylcholine receptor subunit alpha-7 antibody
    see all

Anti-Nicotinic Acetylcholine Receptor alpha 7 antibody 图像

  • ab110851 at 5µg/ml staining Nicotinic Acetylcholine Receptor alpha 7 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-Nicotinic Acetylcholine Receptor alpha 7 antibody (ab110851)参考文献

ab110851 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Mouse Cell (skin)
Specification skin
Fixative perfusion fixation
Permeabilization Yes - Triton X 100
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 22°C
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提交于 Jan 02 2013

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