Anti-Nicotinic Acetylcholine Receptor alpha 3抗体(ab55773)

概述

  • 产品名称Anti-Nicotinic Acetylcholine Receptor alpha 3抗体
    参阅全部 Nicotinic Acetylcholine Receptor alpha 3 一抗
  • 描述
    兔多克隆抗体to Nicotinic Acetylcholine Receptor alpha 3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Dog
  • 免疫原

    A region within synthetic peptide: QNYDPNLRPA ERDSDVVNVS LKLTLTNLIS LNEREEALTT NVWIEMQWCD, corresponding to N terminal amino acids 35-84 of Human Nicotinic Acetylcholine Receptor alpha 3

  • 阳性对照
    • HepG2 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab55773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.625 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 57 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACHA3_HUMAN antibody
    • AChR antibody
    • Cholinergic receptor neuronal nicotinic alpha polypeptide 3 antibody
    • Cholinergic receptor nicotinic alpha 3 antibody
    • Cholinergic receptor nicotinic alpha polypeptide 3 antibody
    • CHRNA 3 antibody
    • CHRNA3 antibody
    • LNCR2 antibody
    • MGC104879 antibody
    • NACHRA 3 antibody
    • NACHRA3 antibody
    • Neuronal acetylcholine receptor protein alpha 3 chain precursor antibody
    • Neuronal acetylcholine receptor subunit alpha 3 antibody
    • Neuronal acetylcholine receptor subunit alpha-3 antibody
    • Neuronal nicotinic acetylcholine receptor alpha 3 subunit antibody
    • PAOD2 antibody
    see all

Anti-Nicotinic Acetylcholine Receptor alpha 3 antibody 图像

  • Anti-Nicotinic Acetylcholine Receptor alpha 3 antibody (ab55773) at 0.625 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000

    Predicted band size : 57 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)

Anti-Nicotinic Acetylcholine Receptor alpha 3 antibody (ab55773)参考文献

This product has been referenced in:
  • Paliwal A  et al. Aberrant DNA methylation links cancer susceptibility locus 15q25.1 to apoptotic regulation and lung cancer. Cancer Res 70:2779-88 (2010). WB ; Human . Read more (PubMed: 20332232) »

See 1 Publication for this product

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