Anti-Nicotinic Acetylcholine Receptor alpha 3抗体(ab110801)

概述

  • 产品名称Anti-Nicotinic Acetylcholine Receptor alpha 3抗体
    参阅全部 Nicotinic Acetylcholine Receptor alpha 3 一抗
  • 描述
    兔多克隆抗体to Nicotinic Acetylcholine Receptor alpha 3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Macaque Monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 350 - 450 of Human Nicotinic Acetylcholine Receptor alpha 3.

  • 阳性对照
    • This antibody gave a positive signal in Human Spinal Cord tissue lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab110801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).

靶标

  • 功能After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 序列相似性Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-3/CHRNA3 sub-subfamily.
  • 细胞定位Cell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ACHA3_HUMAN antibody
    • AChR antibody
    • Cholinergic receptor neuronal nicotinic alpha polypeptide 3 antibody
    • Cholinergic receptor nicotinic alpha 3 antibody
    • Cholinergic receptor nicotinic alpha polypeptide 3 antibody
    • CHRNA 3 antibody
    • CHRNA3 antibody
    • LNCR2 antibody
    • MGC104879 antibody
    • NACHRA 3 antibody
    • NACHRA3 antibody
    • Neuronal acetylcholine receptor protein alpha 3 chain precursor antibody
    • Neuronal acetylcholine receptor subunit alpha 3 antibody
    • Neuronal acetylcholine receptor subunit alpha-3 antibody
    • Neuronal nicotinic acetylcholine receptor alpha 3 subunit antibody
    • PAOD2 antibody
    see all

Anti-Nicotinic Acetylcholine Receptor alpha 3 antibody 图像

  • Anti-Nicotinic Acetylcholine Receptor alpha 3 antibody (ab110801) at 1 µg/ml + Human spinal cord tissue lysate - total protein (ab29188) at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
    Additional bands at : 51 kDa (possible cleavage fragment).

    Exposure time : 8 minutes

Anti-Nicotinic Acetylcholine Receptor alpha 3 antibody (ab110801)参考文献

ab110801 has not yet been referenced specifically in any publications.

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