Anti-NGF抗体(ab10837)

概述

  • 产品名称Anti-NGF抗体
    参阅全部 NGF 一抗
  • 描述
    山羊多克隆抗体to NGF
  • 经测试应用适用于: ELISA, WB, Neutralisingmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Recombinant full length rat NGF beta protein expressed in Sf 21 insect cells.

  • 阳性对照
    • Tested with human erythroleukemic cells (TF-1) expressing recombinant rat NGF beta.

性能

应用

Our Abpromise guarantee covers the use of ab10837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 0.5 - 1 µg/ml.
WB Use a concentration of 0.1 - 0.2 µg/ml. Detects a band of approximately 13.2 kDa.
Neutralising Use a concentration of 0.05 - 0.15 µg/ml.

靶标

  • 功能Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
  • 疾病相关Neuropathy, hereditary sensory and autonomic, 5
  • 序列相似性Belongs to the NGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta nerve growth factor antibody
    • Beta NGF antibody
    • Beta-nerve growth factor antibody
    • Beta-NGF antibody
    • HSAN5 antibody
    • MGC161426 antibody
    • MGC161428 antibody
    • Nerve growth factor (beta polypeptide) antibody
    • Nerve growth factor antibody
    • Nerve growth factor beta antibody
    • Nerve growth factor beta polypeptide antibody
    • Nerve growth factor beta subunit antibody
    • NGF antibody
    • NGF_HUMAN antibody
    • NGFB antibody
    • NID67 antibody
    see all

Anti-NGF antibody (ab10837)参考文献

ab10837 has not yet been referenced specifically in any publications.

Product Wall

Thank you for providing some more useful information about your experimental system. I understand now from your recent e-mail, that you used Cos-7 cells (monkey) transfected with a vector carrying the coding part of the human NGFb gene. I have disc...

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