Anti-NFYB/CBF-B抗体(ab6559)
Key features and details
- Rabbit polyclonal to NFYB/CBF-B
- Suitable for: ELISA, IP, EMSA, WB
- Reacts with: Mouse, Human
- Isotype: IgG
概述
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产品名称
Anti-NFYB/CBF-B抗体
参阅全部 NFYB/CBF-B 一抗 -
描述
兔多克隆抗体to NFYB/CBF-B -
宿主
Rabbit -
经测试应用
适用于: ELISA, IP, EMSA, WBmore details -
种属反应性
与反应: Mouse, Human -
免疫原
Synthetic peptide corresponding to NFYB/CBF-B (N terminal) conjugated to keyhole limpet haemocyanin.
Sequence:QQISGVQQIQFS
Database link: NP_000729.2 -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
Preservative: 0.01% Sodium azide
Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate -
Concentration information loading...
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纯度
IgG fraction -
纯化说明
This product was prepared from monospecific antiserum by delipidation and defibrination. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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EMSA |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
|
说明 |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
EMSA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
靶标
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功能
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. -
序列相似性
Belongs to the NFYB/HAP3 subunit family. -
结构域
Can be divided into 3 domains: the weakly conserved A domain, the highly conserved B domain thought to be involved in subunit interaction and DNA binding, and the Glu-rich C domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 4801 Human
- Entrez Gene: 18045 Mouse
- Omim: 189904 Human
- SwissProt: P25208 Human
- SwissProt: P63139 Mouse
- Unigene: 84928 Human
- Unigene: 245998 Mouse
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别名
- CAAT box DNA binding protein subunit B antibody
- CAAT box DNA-binding protein subunit B antibody
- CBF A antibody
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab6559 被引用在 4 文献中.
- Braden CR & Neufeld TP Atg1-independent induction of autophagy by the Drosophila Ulk3 homolog, ADUK. FEBS J 283:3889-3897 (2016). PubMed: 27717182
- Su B et al. Interleukin-1ß/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis. Hepatology 61:585-97 (2015). PubMed: 25294684
- Huang Y et al. Phospho-?Np63a is a key regulator of the cisplatin-induced microRNAome in cancer cells. Cell Death Differ 18:1220-30 (2011). WB ; Human . PubMed: 21274007
- Grskovic M et al. Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells. PLoS Genet 3:e145 (2007). EMSA ; Mouse . PubMed: 17784790