Anti-NFIL3抗体(ab1078)

概述

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab1078 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Detects a band of approximately 53 kDa (predicted molecular weight: 51 kDa).Can be blocked with Human NFIL3 peptide (ab22793).

靶标

  • 功能Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity). Represses transcriptional activity of PER1 (By similarity). Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity). Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity). Protects pro-B cells from programmed cell death.
  • 组织特异性Expressed in bladder stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and muscle.
  • 序列相似性Belongs to the bZIP family. NFIL3 subfamily.
    Contains 1 bZIP domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • E4 promoter binding protein 4 antibody
    • E4 promoter-binding protein 4 antibody
    • E4BP 4 antibody
    • E4BP4 antibody
    • E4BP4 protein antibody
    • IL3BP 1 antibody
    • IL3BP1 antibody
    • Interleukin 3 binding protein 1 antibody
    • Interleukin 3 promoter transcriptional activator antibody
    • Interleukin-3 promoter transcriptional activator antibody
    • Interleukin-3-binding protein 1 antibody
    • NFIL 3 antibody
    • NFIL 3A antibody
    • NFIL3 antibody
    • NFIL3_HUMAN antibody
    • NFIL3A antibody
    • Nuclear factor interleukin 3 regulated antibody
    • Nuclear factor interleukin-3-regulated protein antibody
    • Transcriptional activator NF IL3A antibody
    • Transcriptional activator NF-IL3A antibody
    see all

Anti-NFIL3 antibody 图像

  • Anti-NFIL3 antibody (ab1078) at 0.5 µg/ml + Cell lysate prepared from HepG2 cells at 20 µg
    Developed using the ECL technique

    Predicted band size : 51 kDa

Anti-NFIL3 antibody (ab1078)参考文献

ab1078 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. We are very sorry to hear that you are still having difficulty with this antibody. Generally, it is true that PCR results can provide information about the presence of mRNA of a particular target. However, the positive re...

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Dear Dr Salerno I do apologise for my geographical blunder and I hope I haven't caused too much offence. Shipping ab1078 to New Zealand is relatively straight forward. The transit time is about 4 days and shipping charge is GBP45.00. The price again...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"