功能Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
序列相似性Belongs to the CTF/NF-I family. Contains 1 CTF/NF-I DNA-binding domain.
Anti-NFIC antibody (ab89516) at 1/500 dilution + HeLa nuclear extracts at 50 µg
Predicted band size : 56 kDa
Anti-NFIC antibody (ab89516)参考文献
This product has been referenced in:
Li D et al. Inhibition of AHR transcription by NF1C is affected by a single-nucleotide polymorphism, and is involved in suppression of human uterine endometrial cancer. Oncogene : (2012).
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