概述

  • 产品名称NF023
  • 描述
    Competitive P2X1 receptor antagonist
  • 生物学描述Suramin analog and subtype-selective competitive antagonist at P2X1 receptors (IC50 values are 0.21, 28.9, >50 and >100 μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses, respectively). Inhibits contraction induced by electrical field stimulation in smooth muscle.
  • 纯度> 96%

性能

    NF023 (ab120454)参考文献

    This product has been referenced in:
    • Cho YR  et al. P2X and P2Y Receptors Mediate Contraction Induced by Electrical Field Stimulation in Feline Esophageal Smooth Muscle. Korean J Physiol Pharmacol 14:311-6 (2010). Read more (PubMed: 21165330) »
    • Soto F  et al. Antagonistic properties of the suramin analogue NF023 at heterologously expressed P2X receptors. Neuropharmacology 38:141-9 (1999). Read more (PubMed: 10193905) »
    • Ralevic V & Burnstock G Receptors for purines and pyrimidines. Pharmacol Rev 50:413-92 (1998). Read more (PubMed: 9755289) »

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