概述

  • 产品名称Anti-Neurturin抗体
    参阅全部 Neurturin 一抗
  • 描述
    山羊多克隆抗体to Neurturin
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Cow, Dog, Rhesus monkey
  • 免疫原

    Synthetic peptide:

    C-DAHSRYHTVHELSARE

    , corresponding to C terminal amino acids 178-193 of Human Neurturin (NP_004549.1).

  • 阳性对照
    • Human and Mouse Heart lysates.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab77280 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunising peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab77280 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Antibody detection limit dilution: 1/64000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 25 kDa (predicted molecular weight: 22 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
    • 疾病相关Defects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
    • 序列相似性Belongs to the TGF-beta family. GDNF subfamily.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Neurturin antibody
      • Neurturin precursor antibody
      • NRTN antibody
      • NRTN_HUMAN antibody
      • NTN antibody
      • prepro-neurturin antibody
      see all

    Anti-Neurturin antibody 图像

    Anti-Neurturin antibody (ab77280)参考文献

    ab77280 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"