概述

  • 产品名称Anti-Neurturin抗体
    参阅全部 Neurturin 一抗
  • 描述
    兔多克隆抗体to Neurturin
  • 经测试应用适用于: ELISA, IHC-P, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant full length protein (Human)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: Whole serum
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab49203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
IHC-P
IHC-Fr
  • 应用说明1 site ELISA: 1/5000.
    IHC-Fr: 1/2000.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
    • 疾病相关Defects in NRTN are a cause of Hirschsprung disease (HSCR) [MIM:142623]. In association with mutations of RET gene, and possibly with other loci, defects in NRTN are involved in Hirschsprung disease. This genetic disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
    • 序列相似性Belongs to the TGF-beta family. GDNF subfamily.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Neurturin antibody
      • Neurturin precursor antibody
      • NRTN antibody
      • NRTN_HUMAN antibody
      • NTN antibody
      • prepro-neurturin antibody
      see all

    Anti-Neurturin antibody 图像

    • ab49203 staining Neurturin in Human cochleae tissue sections by Immunohistochemistry. Samples were incubated with primary antibody (1/100) for 20 hours at 4°C. Positive Neuturin immunostaining was found in the spiral ganglion cell bodies and nerve fibers. The circle indicates peripheral nerve processes, arrows point to the nerve bundles of the central processes. 

    Anti-Neurturin antibody (ab49203)参考文献

    This product has been referenced in:
    • Liu W & Rask-Andersen H Immunohistological analysis of neurturin and its receptors in human cochlea. Auris Nasus Larynx N/A:N/A (2013). IHC-P, IHC-Fr ; Human . Read more (PubMed: 24139947) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"