Anti-Neurotrophin 4抗体(ab6205)

概述

  • 产品名称Anti-Neurotrophin 4抗体
    参阅全部 Neurotrophin 4 一抗
  • 描述
    兔多克隆抗体to Neurotrophin 4
  • 特异性Less than 1% cross reactivity against NGF, BDNF and NT3 by dot blot. Cross reactivity: Known to react with human NT4. Not yet tested against other species.
  • 经测试应用适用于: Dot blot, ELISA, IHC-Fr, Neutralising, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human).

  • 常规说明The concentrations of NT4 are generally very low in most tissues. A good positive control is neonatal testes of rat (Zhang et al, 1999). This antibody has been shown useful for quantitative ELISA, immunohistochemistry of lesioned brain as well as for western blot and inhibition of biological activity

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab6205 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot
ELISA
IHC-Fr
Neutralising
WB
  • 应用说明Immunohistochemistry: 1-2 ug/ml
    Western Blot: 1-2 ug/ml
    Immunoblot: 1-2 ug/ml
    1 site ELISA: 0.5 ug/ml
    Biological Inhibition: 2-10 ug/ml (ED50)
  • 靶标

    • 功能Target-derived survival factor for peripheral sensory sympathetic neurons.
    • 组织特异性Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues.
    • 疾病相关Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place.
    • 序列相似性Belongs to the NGF-beta family.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • GLC10 antibody
      • GLC1O antibody
      • Neurotrophic factor 4 antibody
      • Neurotrophic factor 5 antibody
      • Neurotrophin 4/5 antibody
      • Neurotrophin 5 (neurotrophin 4/5) antibody
      • Neurotrophin 5 antibody
      • Neurotrophin-4 antibody
      • Neurotrophin-5 antibody
      • Neutrophic factor 4 antibody
      • Neutrophic factor 5 antibody
      • NT 4 antibody
      • NT 4/5 antibody
      • NT 5 antibody
      • NT-4 antibody
      • NT-5 antibody
      • NT4 antibody
      • NT4/5 antibody
      • NT4P antibody
      • NT5 antibody
      • NTF4 antibody
      • NTF4_HUMAN antibody
      • NTF5 antibody
      see all

    Anti-Neurotrophin 4 antibody (ab6205)参考文献

    ab6205 has not yet been referenced specifically in any publications.

    Product Wall

    ab6204 and ab6205 are both suitable for detecting neurotrophin 4/5 using immunohistochemistry, but we recommend ab6205 which is the affinity purified version of ab6204 and therefore likely to give less background.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"