Anti-Neuroligin 2抗体(ab77595)

概述

  • 产品名称
    Anti-Neuroligin 2抗体
    参阅全部 Neuroligin 2 一抗
  • 描述
    山羊多克隆抗体to Neuroligin 2
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse, Dog
  • 免疫原

    Synthetic peptide:

    NPPDTDIRDPGKK

    , corresponding to internal sequence amino acids 165-177 of Human Neuroligin 2 (NP_065846.1).

  • 阳性对照
    • Human Pancreas lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab77595 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 91 kDa). An additional band of unknown identity was also consistently observed at 50kDa. This band was successfully blocked by incubation with the immunising peptide.

靶标

  • 相关性
    Neuroligins are cell adhesion proteins that are thought to instruct the formation and alignment of synaptic specializations. The three known rodent neuroligin isoforms share homologous extracellular acetylcholinesterase-like domains that bridge the synaptic cleft and bind beta-neurexins. All neuroligins have identical intracellular C-terminal motifs that bind to PDZ domains of various target proteins. Neuroligin 2 is exclusively localized to inhibitory synapses in rat brain and dissociated neurons. In immature neurons, neuroligin 2 is found at synapses and also at GABAA receptor aggregates that are not facing presynaptic termini.
  • 细胞定位
    Cell Membrane
  • 数据库链接
  • 别名
    • KIAA1366 antibody
    • MGC67386 antibody
    • NL2 antibody
    • NLGN2 antibody
    • Ortholog of human and rat neuroligin 2 NLGN2 antibody
    • OTTHUMP00000135277 antibody
    • OTTMUSP00000006214 antibody
    • RP23-422L16.24 antibody
    see all

图片

  • Anti-Neuroligin 2 antibody (ab77595) at 2 µg/ml + Human Pancrease lysate (in RIPA buffer) at 35 µg

    Predicted band size : 91 kDa

    Primary incubation was 1 hour.

    Detected by chemiluminescence.

实验方案

文献

ab77595 has not yet been referenced specifically in any publications.

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