Anti-Neurokinin 3 Receptor NK3抗体(ab124025)

概述

  • 产品名称Anti-Neurokinin 3 Receptor NK3抗体
    参阅全部 Neurokinin 3 Receptor NK3 一抗
  • 描述
    兔多克隆抗体to Neurokinin 3 Receptor NK3
  • 特异性ab124025 does not recognise NK1R or NK2R.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    An 18 amino acid peptide from near the center of Human Neurokinin 3 Receptor NK3.

  • 阳性对照
    • Human brain tissue; RAW 264.7 whole cell lysate
  • 常规说明This product should be stored undiluted.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
  • 存储溶液Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab124025 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 52 kDa).Can be blocked with Neurokinin 3 Receptor NK3 peptide (ab176411).
IHC-P Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.
  • 疾病相关Hypogonadotropic hypogonadism 11 with or without anosmia
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MGC148060 antibody
    • MGC148061 antibody
    • Neurokinin B receptor antibody
    • Neurokinin beta receptor antibody
    • Neuromedin K Receptor antibody
    • Neuromedin-K receptor antibody
    • NK 3 receptor antibody
    • NK 3R antibody
    • NK-3 receptor antibody
    • NK-3R antibody
    • NK3 receptor antibody
    • NK3R antibody
    • NK3R_HUMAN antibody
    • NKR antibody
    • TAC 3R antibody
    • TAC3R antibody
    • TAC3RL antibody
    • Tachykinin receptor 3 antibody
    • TACR 3 antibody
    • Tacr3 antibody
    see all

Anti-Neurokinin 3 Receptor NK3 antibody 图像

  • Lane 1 : Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) at 0.5 µg/ml
    Lane 2 : Anti-Neurokinin 3 Receptor NK3 antibody (ab124025) at 2 µg/ml

    Lane 1 : RAW 264.7 whole cell lysate
    Lane 2 : RAW 264.7 whole cell lysate


    Predicted band size : 52 kDa
    Observed band size : 46 kDa (why is the actual band size different from the predicted?)
  • ab124025, at 5µg/ml, staining Neurokinin 3 Receptor NK3 in paraffin-embedded Human brain tissue by Immunohistochemistry.

Anti-Neurokinin 3 Receptor NK3 antibody (ab124025)参考文献

ab124025 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample Human Tissue sections (Nasal mucosa)
Antigen retrieval step None
Permeabilization No
Specification Nasal mucosa
Blocking step Serum as blocking agent for 45 minute(s) · Concentration: 5 · Temperature: RT°C
Fixative Zamboni
Username

Mr. Duc Dung Le

Verified customer

提交于 Apr 29 2015

Application Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample Mouse Tissue sections (Brain)
Antigen retrieval step None
Specification Brain
Blocking step Serum as blocking agent for 45 minute(s) · Concentration: 5% · Temperature: RT°C
Username

Mr. Duc Dung Le

Verified customer

提交于 Apr 29 2015

Thank you for taking the time to complete our questionnaires and contact us. I am sorry to hearthe customer has had difficulty obtaining satisfactory results from these antibodies.

The details you have kindly provided will enable us to inves...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"