概述

  • 产品名称Anti-Neurokinin 1 Receptor抗体
    参阅全部 Neurokinin 1 Receptor 一抗
  • 描述
    兔多克隆抗体to Neurokinin 1 Receptor
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    A synthetic peptide derived from internal sequence of human Neurokinin 1 Receptor.

  • 阳性对照
    • Jurkat cell extracts.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab75516 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
WB 1/500 - 1/1000. Predicted molecular weight: 46 kDa.

靶标

  • 功能This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Neurokinin 1 antibody
    • NK 1 receptor antibody
    • NK 1R antibody
    • NK-1 receptor antibody
    • NK-1R antibody
    • NK1 receptor antibody
    • NK1R antibody
    • NK1R_HUMAN antibody
    • NKIR antibody
    • SPR antibody
    • Substance P receptor antibody
    • Substance-P receptor antibody
    • TAC 1R antibody
    • TAC1R antibody
    • Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor) antibody
    • Tachykinin receptor 1 (substance P receptor neurokinin 1 receptor) antibody
    • Tachykinin receptor 1 antibody
    • TACR1 antibody
    see all

Anti-Neurokinin 1 Receptor antibody 图像

  • All lanes : Anti-Neurokinin 1 Receptor antibody (ab75516) at 1/500 dilution

    Lane 1 : Jurkat cell extract
    Lane 2 : Jurkat cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 46 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 19 kDa,60 kDa,85 kDa. We are unsure as to the identity of these extra bands.

Anti-Neurokinin 1 Receptor antibody (ab75516)参考文献

This product has been referenced in:
  • Chauhan VS  et al. Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis. J Immunol 186:7255-63 (2011). WB ; Mouse . Read more (PubMed: 21562162) »

See 1 Publication for this product

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