Anti-Neurogenin3抗体[OTI3B5] (ab87108)


  • 产品名称Anti-Neurogenin3抗体[OTI3B5]
    参阅全部 Neurogenin3 一抗
  • 描述
    小鼠单克隆抗体[OTI3B5] to Neurogenin3
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Protein expressed in 293T cells transfected with Human Neurogenin3 expression vector.

  • 阳性对照
    • Transiently transfected HEK293T cell lysate. Human liver tissue. Transiently transfected HeLa cells.
  • 常规说明

    The clone number has been updated from 3B5 to OTI3B5, both clone numbers name the same clone.



Our Abpromise guarantee covers the use of ab87108 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/2000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
IHC-P Use at an assay dependent concentration.
ICC/IF 1/100.


  • 功能Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types.
  • 疾病相关Defects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells.
  • 序列相似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ATH4B antibody
    • Atoh5 antibody
    • bHLHa7 antibody
    • Class A basic helix-loop-helix protein 7 antibody
    • Math4B antibody
    • NEUROG3 antibody
    • Neurogenin-3 antibody
    • NGN-3 antibody
    • ngn3 antibody
    • NGN3_HUMAN antibody
    • OTTHUMP00000019730 antibody
    • Protein atonal homolog 5 antibody
    see all

Anti-Neurogenin3 antibody [OTI3B5] 图像

  • All lanes : Anti-Neurogenin3 antibody [OTI3B5] (ab87108) at 1/2000 dilution

    Lane 1 : HEK293T cells transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cells transfected with pCMV6-ENTRY Neurogenin3 cDNA

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 23 kDa
    Observed band size : 23 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC200097)
  • ab87108 immunofluorescent staining of HeLa cells transiently transfected by pCMV6-ENTRY NEUROG3.
  • Immunohistochemical staining of paraffin-embedded Human lymph node tissue using ab87108.

Anti-Neurogenin3 antibody [OTI3B5] (ab87108)参考文献

This product has been referenced in:
  • Shaer A  et al. miR-375 induces human decidua basalis-derived stromal cells to become insulin-producing cells. Cell Mol Biol Lett 19:483-99 (2014). Human . Read more (PubMed: 25169436) »

See 1 Publication for this product

Product Wall

Thank you for your reply and for providing the order number.

Your credit note ID is *.

I am sorry that these antibodiesdid not perform as stated on the datasheets. If payment has already been made on the original order and y...

Read More

Thank you for your reply.

I would be happy to process a refund for you, since these antibodies are covered under our Abpromise, which is good for 6 months after purchase. To be able to process the refund, could you please provide me with the e...

Read More

Thank you for your reply.

What I meant by different targets against the same antibody, is that we sometimes have multiply antibodies that recognize the same target in our catalogue.

However, of the 3 antibodies you are using, the only...

Read More

Thank you for your reply and for providing the protocol information.

Based on what you have described, I think that the best way forward in this issue is send free of charge replacements for the antibodies in question. I could either replace ...

Read More

Thank you for contacting Abcam.

I am sorry that you are having some technical issues with a few of our antibodies. These antibodiesare covered under our Abpromise for six months andareguaranteed to work in IHC-P on human samples . If we canno...

Read More

Thank you for your patience.

The lab has retested ab87108 and new images will be available on the datasheet shortly. There thestaining can be seen in the nucleus only.

I hope this information is helpful to you. Please do not hesita...

Read More

Thank you for your patience.

The supplying lab of ab87108 let me know that theirantibody team has reviewed the data you were refering to, and is going to re-test this antibody for IHC. It may take one week longer until we receive those resul...

Read More

Thank you for contacting us.

I have contacted the lab regarding the 4 antibodies you had inquired about, and will be in touch with more informaton as soon as I have it.

Thank you for your patience!

Use our products...

Read More

いつもお世話になっております。 この製品の染色について回答させていただきます。 ラボに確認し、データシートに記載されている[Cellular localization - Nuclear]情報はSwissProtのデータベース(よりとられております。この情報を確認してみると、実は核の染色は実験で確認された結果ではないようでございます。しかし、核が染まるか、細胞質が染まるか、全く情報がございません。 それから...

Read More