概述

  • 产品名称Anti-NEURL2抗体
    参阅全部 NEURL2 一抗
  • 描述
    兔多克隆抗体to NEURL2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 143-192 (

    VEPYLRIEQFRIPRDRLVGRSRPGLYSHLLDQLYELNVLPPTARRSRLGV

    ) of Human NEURL2 (NP_542787).

  • 阳性对照
    • Human Placenta Lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab99125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 32 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.
  • 组织特异性Expressed specifically in skeletal and cardiac muscles.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 NHR (neuralized homology repeat) domain.
    Contains 1 SOCS box domain.
  • 结构域The SOCS domain mediates the interaction with TCEB1 and TCEB2, while the NHR domain may be involved in ubiquitination substrate binding.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • NEUL2_HUMAN antibody
    • Neuralized like protein 2 antibody
    • Neuralized-like protein 2 antibody
    • NEURL2 antibody

Anti-NEURL2 antibody 图像

  • Anti-NEURL2 antibody (ab99125) at 1 µg/ml + Human Placenta Lysate at 10 µg

    Predicted band size : 32 kDa

Anti-NEURL2 antibody (ab99125)参考文献

ab99125 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab99125.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"