概述

  • 产品名称Anti-Neurabin 1抗体
    参阅全部 Neurabin 1 一抗
  • 描述
    兔多克隆抗体to Neurabin 1
  • 经测试应用适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Rat, Human, Xenopus laevis
  • 免疫原

    Recombinant fragment corresponding to Rat Neurabin 1. Bacterially expressed coiled-coil domain of Rat neurabin I.

  • 阳性对照
    • WB: rat brain extract. ICC/IF: rat hippocampal cells.

性能

应用

Our Abpromise guarantee covers the use of ab3483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration.

Immunofluorescence staining of Neurabin 1 in cultured rat hippocampal cells results in diffuse cytoplasmic staining.

WB 1/1000. Detects a band of approximately 123 kDa (predicted molecular weight: 123 kDa).

靶标

  • 功能Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.
  • 序列相似性Contains 1 PDZ (DHR) domain.
    Contains 1 SAM (sterile alpha motif) domain.
  • 结构域Interacts with p70-S6K via its PDZ domain.
  • 细胞定位Cytoplasm > cytoskeleton. Cell junction > synapse > synaptosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ20068 antibody
    • KIAA1222 antibody
    • NEB1_HUMAN antibody
    • Neurabin I antibody
    • Neurabin-1 antibody
    • Neurabin-I antibody
    • Neurabin1 antibody
    • NeurabinI antibody
    • Neural tissue specific F actin binding protein I antibody
    • Neural tissue-specific F-actin-binding protein I antibody
    • NRB 1 antibody
    • NRB I antibody
    • NRB1 antibody
    • NRBI antibody
    • Ppp1r9a antibody
    • Protein phosphatase 1 regulatory (inhibitor) subunit 9A antibody
    • Protein phosphatase 1 regulatory subunit 9A antibody
    see all

Anti-Neurabin 1 antibody 图像

  • Immunolocalization of neurabin-1 in human brain tissue using ab3483.

Anti-Neurabin 1 antibody (ab3483)参考文献

This product has been referenced in:
  • Grgic I  et al. Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo. Kidney Int N/A:N/A (2014). Human . Read more (PubMed: 24940801) »

See 1 Publication for this product

Product Wall

Merci pour ce complément d'informations qui va nous permettre de chercher l'origine du problème rencontré avec le ab134081.

Comme convenu j'ai mis en place l'envoi d'une unité de ab3483 et d'une unité de lysa...

Read More
Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Xenopus laevis Cell (cultured retinal ganglion cell growth cone)
Specification cultured retinal ganglion cell growth cone
Fixative Paraformaldehyde
Permeabilization Yes - 0.1% triton x-100
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
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提交于 Dec 03 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"