概述

  • 产品名称Anti-Netrin 1抗体
    参阅全部 Netrin 1 一抗
  • 描述
    兔多克隆抗体to Netrin 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Zebrafish
    预测可用于: Rat, Human, Pig, Xenopus laevis
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 - 200 of Mouse Netrin 1.

  • 阳性对照
    • This antibody gave a positive signal in Mouse Fetus (14 Day Old) Tissue Lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab78854 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 68 kDa).
    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
    • 组织特异性Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
    • 序列相似性Contains 3 laminin EGF-like domains.
      Contains 1 laminin N-terminal domain.
      Contains 1 NTR domain.
    • 细胞定位Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • 数据库链接
    • 别名
      • epididymis tissue protein Li 131P antibody
      • NET1_HUMAN antibody
      • Netrin 1, mouse, homolog of antibody
      • Netrin 1-like antibody
      • Netrin-1 antibody
      • Netrin1 antibody
      • Ntn 1 antibody
      • NTN 1L antibody
      • NTN1 antibody
      • NTN1L antibody
      • Unc6 antibody
      see all

    Anti-Netrin 1 antibody 图像

    • Anti-Netrin 1 antibody (ab78854) at 1 µg/ml + Mouse Fetus (14 Day Old) Tissue Lysate at 10 µg

      Secondary
      Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
      Developed using the ECL technique

      Performed under reducing conditions.

      Predicted band size : 68 kDa
      Observed band size : 72 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 25 kDa. We are unsure as to the identity of these extra bands.

      Exposure time : 3 minutes

    Anti-Netrin 1 antibody (ab78854)参考文献

    This product has been referenced in:
    • Liao SJ  et al. Netrin-1 rescues neuron loss by attenuating secondary apoptosis in ipsilateral thalamic nucleus following focal cerebral infarction in hypertensive rats. Neuroscience 231:225-32 (2013). Read more (PubMed: 23232257) »

    See 1 Publication for this product

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