概述

  • 产品名称Anti-Netrin 1抗体
    参阅全部 Netrin 1 一抗
  • 描述
    山羊多克隆抗体to Netrin 1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Chicken, Xenopus laevis, Zebrafish
  • 免疫原

    Synthetic peptide:

    KFQQREKKGKCKKA

    , corresponding to C terminal amino acids 591-604 of Human Netrin 1 (NP_004813.2).

  • 阳性对照
    • Human brain (cerebellum), Mouse and Rat brain lysates

性能

应用

Our Abpromise guarantee covers the use of ab106929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 68 kDa).

靶标

  • 功能Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
  • 组织特异性Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
  • 序列相似性Contains 3 laminin EGF-like domains.
    Contains 1 laminin N-terminal domain.
    Contains 1 NTR domain.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • epididymis tissue protein Li 131P antibody
    • NET1_HUMAN antibody
    • Netrin 1, mouse, homolog of antibody
    • Netrin 1-like antibody
    • Netrin-1 antibody
    • Netrin1 antibody
    • Ntn 1 antibody
    • NTN 1L antibody
    • NTN1 antibody
    • NTN1L antibody
    • Unc6 antibody
    see all

Anti-Netrin 1 antibody 图像

  • Anti-Netrin 1 antibody (ab106929) at 0.5 µg/ml + Rat brain lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 68 kDa
    Observed band size : ~70 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

Anti-Netrin 1 antibody (ab106929)参考文献

ab106929 has not yet been referenced specifically in any publications.

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