Anti-Netrin 1抗体[158936] (ab50266)

概述

  • 产品名称Anti-Netrin 1抗体[158936]
    参阅全部 Netrin 1 一抗
  • 描述
    小鼠单克隆抗体[158936] to Netrin 1
  • 特异性This antibody shows 100% cross-reactivity with rchNetrin-1 and no cross reactivity with rchNetrin-2, rhNetrin-4, rmNetrin-4 or rmNetrin-G1a.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Recombinant full length protein (Mouse)

性能

应用

Our Abpromise guarantee covers the use of ab50266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Direct ELISA: Use at a concentration of 0.5 - 1 µg/ml.
    WB: Use at a concentration of 1 - 2 µg/ml. Predicted molecular weight: 68 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
    • 组织特异性Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas.
    • 序列相似性Contains 3 laminin EGF-like domains.
      Contains 1 laminin N-terminal domain.
      Contains 1 NTR domain.
    • 细胞定位Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • 数据库链接
    • 别名
      • epididymis tissue protein Li 131P antibody
      • NET1_HUMAN antibody
      • Netrin 1, mouse, homolog of antibody
      • Netrin 1-like antibody
      • Netrin-1 antibody
      • Netrin1 antibody
      • Ntn 1 antibody
      • NTN 1L antibody
      • NTN1 antibody
      • NTN1L antibody
      • Unc6 antibody
      see all

    Anti-Netrin 1 antibody [158936] (ab50266)参考文献

    ab50266 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your enquiry regarding ab50266.
    The immunogen used to raise this monoclonal antibody was a recombinant full length protein (mouse). The exact epitope sequence has not been mapped yet. As soon as we have further details, we will updat...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"